The Lysosomal Disease Network (LDN) continues its Pilot Project program designed to increase intra-consortium research endeavors.

Currently, each of the research studies within the LDN are operated at one primary site; some LDN projects have sub-sites operating under the primary proposal (6703, 6705, 6722, 6728) but projects operating at more than one site are the exception rather than the rule. In contrast, almost all other consortia within the Rare Diseases Clinical Research Network (RDCRN) conduct a proscribed number of studies, designed by the consortium PI, at several affiliated sites.

We believe that continued NIH funding will be enhanced by greater connectivity within the LDN. To foster a new model for rare disease research, the LDN announces a Pilot Project program. All applications must:

  1. Include a maximum number of sites that exist currently as leading centers for LDN Projects.
  2. The Pilot Project should lead to a project proposal in the next LDN NIH grant application.
  3. A total of $30-$60k (total costs) per year will be available for two years.
  4. Applications are due (TBD).
  5. Funding will commence (TBD).

Any Investigator who feels he/she can meet the demands of the RFA but is not currently a part of the LDN and does not have knowledge of the Rare Disease Clinical Research Network process should contact Brenda Diethelm-Okita (dieth001@nullumn.edu) for more information.

Applications must be on NIH 398 (http://grants.nih.gov/grants/funding/phs398/phs398.html) forms and adhere to the page limitations listed below. Biosketches and budgets must be included.

Applications must include the following:
Specific Aims – 1 Page
Research Strategy (Significance, Innovation, Approach) – 6 Pages
Biosketch for applicant and mentor – 4 Pages each

Awards will be announced (TBD).